A self-splicing intron in the small subunit rRNA gene of Pneumocystis carinii.

نویسندگان

  • M L Sogin
  • J C Edman
چکیده

The coding region for the Pneumocystis carinii small subunit rRNA (16S-like rRNA) contains 390 extra base pairs in a region that is highly conserved in other eukaryotic rRNA genes. The sequence has all the elements characteristic of group I self-splicing introns and interrupts the phylogenetically conserved helix proximal to the 3' terminus of the 16S-like rRNA. In vitro transcripts containing the putative group I intron were capable of undergoing a "self-splicing" reaction which required the presence of guanine nucleotide.

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عنوان ژورنال:
  • Nucleic acids research

دوره 17 13  شماره 

صفحات  -

تاریخ انتشار 1989